![]() What causes the abdominal enlargement seen in Palumboism? ![]() Apart from enlarged abdominal viscera, cardiomegaly can also be a consequence of excessive chronic use of HGH which can result in sudden cardiac death from fatal arrhythmias or heart failure from ventricular hypertrophy of the heart. Similar findings can be found in those abusing HGH. Read Also: HGH and Anti Diabetic drugs, an Anti-Aging Cocktail According to Study The condition can be fatal as it could lead to cardiovascular failure from cardiomyopathy. All of these symptoms are due to abnormal secretion of growth hormone for prolonged durations resulting in enlarged joints, cartilage, organs, hands, and feet. Patients present with complaints of joint pain, progressively increasing shoe or glove size, and even abdominal enlargement. In acromegaly, the condition can take up to 12 years to diagnose due to the gradual progressive disease course. The similarities between Acromegaly and PalumboismĪcromegaly is a result of an abnormality in the pituitary gland such as a pituitary adenoma resulting in excessive secretion of growth hormone. ![]() It can even be thought of as a form of induced acromegaly as it is highly similar to its presentation as well as the underlying mechanism. Due to its multi-organ effect, it results in organomegaly of the visceral organs which is responsible for the enlarged abdomen. Growth Hormone exerts its effects on the entire body and is not just involved in muscle development. Read Also: HGH Benefits: What to Expect From Using Human Growth Hormone Who can be affected by Palumboism?Īlthough the exact pathophysiology of Palumboism is not well understood, it is believed to be due to hypersensitivity to the human growth hormone. Although he never was a professional bodybuilder, he was actively working towards a career in bodybuilding from 1995 to 2004 with a whopping body weight of 300 pounds. Palumboism was named after Dave Palumbo, the first bodybuilder in whom the condition was profound enough to be diagnosed as a consequence of HGH abuse.
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